Reandron vs Testogel: Comparing TRT Options

In Australia, the two most commonly prescribed TRT formulations are Reandron (testosterone undecanoate injection) and Testogel (testosterone gel 1%). Both are PBS-listed, both are effective, and your GP can prescribe either. Here's how they compare.

Reandron (testosterone undecanoate injection)

Reandron is a long-acting intramuscular injection administered every 10–14 weeks. It's the most popular TRT option in Australia, accounting for approximately 50% of all subsidised TRT prescriptions nationally.

• Dosing: One 4ml injection every 10–14 weeks (adjusted based on blood levels)
• Administration: Injected by a GP, nurse, or self-administered (with training)
• PBS cost: ~$30–$40 per injection (with concession: ~$7)
• Private cost: ~$80–$120 per injection
• Steady levels: Good — levels remain relatively stable between injections, though some men notice a dip in the final week before the next dose

Testogel (testosterone gel 1%)

Testogel is a clear, colourless hydroalcoholic gel applied daily to the skin (usually shoulders, upper arms, or abdomen). It delivers testosterone transdermally and is listed on the PBS.

• Dosing: 50mg daily (one sachet), adjusted to 25mg or 100mg based on blood levels
• Administration: Self-applied daily after showering. Must dry before dressing.
• PBS cost: ~$35–$50/month
• Private cost: ~$70–$100/month
• Steady levels: Very stable — daily application maintains consistent testosterone levels with minimal peaks and troughs

Head-to-head comparison

Convenience

Reandron wins on convenience — one injection every 10–14 weeks vs daily application. However, if you dislike needles, Testogel removes that barrier entirely.

Level stability

Testogel provides more consistent daily levels. Reandron can produce a slight peak after injection and a trough before the next dose, though this is generally well-managed with proper timing.

Transfer risk

Testogel carries a risk of skin-to-skin transfer — particularly to women and children. The application site must be covered or washed before close contact. Reandron has no transfer risk.

Cost

Reandron is cheaper annually. At ~$35 per injection, four injections per year costs ~$140. Testogel at ~$40/month costs ~$480/year. For a full cost breakdown, see TRT cost in Australia.

Side effect profile

Both share the same systemic side effect profile (erythrocytosis, oestrogen conversion, etc.). Reandron carries a small risk of injection site reactions and pulmonary oil microembolism. Testogel may cause local skin irritation.

Other options

AndroForte 5% cream: A compounded testosterone cream with higher concentration than Testogel. Not PBS-listed (~$80–$120/month). Preferred by some men and clinicians for its flexibility.

Compounded creams/troches: Available through compounding pharmacies. Useful for non-standard dosing but not PBS-subsidised.

For men concerned about fertility, enclomiphene is an alternative that avoids exogenous testosterone entirely.

Which should you choose?

There's no universally "better" option — it depends on your lifestyle, preferences, and clinical picture. Your GP will recommend the most appropriate formulation based on your blood work, symptoms, and individual circumstances.